Research

 

Bendamustine more effective than chlorambucil for advanced CLL

Bendamustine as a model for the activity of alkylating agents.

Phase I dose finding study evaluating the combination of bendamustine with weekly paclitaxel in patients with pre-treated metastatic breast cancer: RiTa trial. - found that weekly treatment with bendamustine and paclitaxel was feasible for metastatic breast cancer.

A pilot study of bendamustine in advanced bile duct cancer. - Abstract of a German study

Bendamustine in the treatment of chronic lymphocytic leukemia. - Abstract from a German science group.

Salvage chemotherapy for metastatic breast cancer: results of a phase II study with bendamustine. - Study suggested that bendamustine by itself is use in cancer treatment (as opposed to combination with other drugs.)

Weekly administration of bendamustine as salvage therapy in metastatic breast cancer: final results of a phase II study.. - Follow up to above study.

A phase I study of bendamustine hydrochloride administered once every 3 weeks in patients with solid tumors. - Belgian study on the pharmacokinetics of bendamustine, looking at maximum tolerable dose.

Phase II trial of second-line bendamustine chemotherapy in relapsed small cell lung cancer patients. - Again, suggestions that the drug may be effective.